Slides in the "Skin (Heme)" Category

Anaplastic large cell lymphoma, ALK positive

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Clinical summary
52 yo M with skin nodule; also has multiple enlarged lymph glands

Blastic plasmacytoid dendritic cell neoplasm, involving skin

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This slide is part 1 of 2 in the series BPDCN

Clinical history:

Female in her 60’s with pancytopenia and skin lesions. Skin over breast

Immunohistochemistry:

Langerhans cell histiocytosis (skin)

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Clinical history:

12 yo F with tender lump on mid-occipital scalp, gradually increasing in size over 3 months. Mass extended into skull.

Immunohistochemistry:

Mycosis fungoides, plaque stage

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Clinical summary
65 year old gentleman with history of MF (diagnosed in El Salvador). Biopsy to confirm CTCL with progression to Sézary syndrome.

Rosai-Dorfman disease (skin)

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62 y/o female with a 2 cm abdominal skin nodule

Subcutaneous panniculitis-like T cell lymphoma

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Clinical history

33 y/o male with an indurated subcutaneous lesion of the thigh

Immunohistochemistry

Xanthogranuloma, juvenile type

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69 y/o female with a subcutaneous mass of the left elbow