Author "Russell Ryan, M.D." Page

Author Nick: Russell Ryan, M.D.
Name: Russell Ryan


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Langerhans cell histiocytosis (bone)

Tibial lesion in young child

Gastric adenocarcinoma, signet ring cell / diffuse type

22 y/o female with stomach ache

Endocervical adenocarcinoma, metastatic to ovary

46 y/o female. Bilateral ovarian tumors, one 8.0 cm, the other 3 cm. Solid & cystic.

Leiomyoma, with apoplectic change

Middle-aged woman, uterine mass

Malignant mesothelioma, peritoneal

57 y/o female. 10 cm left pelvic sidewall mass.

Brenner tumor, borderline

75 y/o female. 23 cm multicystic ovarian mass with numerous papillary excrescences lining cysts

Mullerian mucinous borderline tumor

28 y/o female. 10 cm, bilocular cystic ovarian mass.

Sertoli-leydig cell tumor, intermediate differentiation, retiform variant

7 y/o female with a 15 cm unilateral ovarian tumor. Solid & cystic sectioned surface.

Low grade cribriform cystadenoma (low grade salivary duct carcinoma)

79 y/o female with parotid mass

Mucoepidermoid carcinoma, sclerosing variant

25 y/o female with parotid lesion

Warthin tumor, infarcted

56 y/o male with prior salivary gland lesion biopsied

Chronic sialadenitis, consistent with Sjogren’s syndrome

76 y/o female with dry mouth

Extraskeletal myxoid chondrosarcoma

Adolescent female with a wrist mass

Infantile fibrosarcoma

Leg mass in deep soft tissues of young child

Alveolar rhabdomyosarcoma

Large mass in extremity of young child

Embryonal rhabdomyosarcoma (sarcoma botryoides)

Rapidly growing mass in orbit of young child

Calcifying aponeurotic fibroma

Toe lesion in young child

AKA: Calcifiying fibromatosis

Infantile digital fibromatosis

Mass of distal toe in 3 month old.

AKA: Inclusion body fibromatosis

Fibrous hamartoma of infancy

Axillary lesion in 6 month old child

Citrobacter infection, fetal lungs

Intrauterine fetal demise at 22 weeks.

Villus edema

Preterm delivery at 30 weeks

Associated with an increased risk of cerebral palsy.

Syphilitic placentitis

Delivery at 38 wks with HIV+ mom, intrauterine growth restriction, and heavy placenta

Pseudopolyp of decidua

Twin at term; nodule noted in dividing membrane

Adrenal medullary cytomegaly, c/w Beckwith-Wideman syndrome

Female fetus delivered prematurely at 24 weeks due to premature rupture of membranes and labor, liveborn but died in immediate neonatal period. Autopsy found hemihypertrophy, macroglossia, and a very heavy placenta at 560g. Cystic mass noted in pancreas.

Read more on Adrenal medullary cytomegaly, c/w Beckwith-Wideman syndrome…

Infantile myofibroma

Tibial mass in 4 month old boy

Acute chorioamnionitis, maternal stage 2, grade 2, fetal stage 2, grade 1

G4P2, gestational age 40.7 weeks, meconium-stained fluid, GBS negative. Placental parenchyma.

Acute chorioamnionitis, maternal stage 2, grade 2, fetal stage 2, grade 1

G4P2, gestational age 40.7 weeks, meconium-stained fluid, GBS negative. Cord and membrane roll.

Acute chorioamnionitis, maternal stage 3, grade 2 AND acute villous edema

Preterm, premature rupture of membranes at 27.4 weeks. Gestational diabetes, insulin required.

Fetal thrombotic vasculopathy AND placental infarcts

Intrauterine fetal demise at 34.6 weeks. Maternal hypertension. Gestational diabetes.

Toxoplasmosis, placental

Intrauterine fetal demise due to infection, mother has a cat

Membranous insertion of umbilical cord

Placenta. No history

Maternal floor infarction

Placenta. No history

Medullary thyroid carcinoma metastatic to liver

This slide is part 2 of 2 in the series Multiple Endocrine Neoplasia 2A

56 y/o M with MEN2A, FDG-avid liver and left adrenal lesions. Mildly elevated norepinephrine of 100 (nl<80). Liver biopsy.

Adrenal cortical and medullary hyperplasia, with micropheochromocytoma

This slide is part 1 of 2 in the series Multiple Endocrine Neoplasia 2A

56 y/o M with MEN2A, FDG-avid liver and left adrenal lesions. Mildly elevated norepinephrine of 100 (nl<80). Left adrenal.

Adrenal cortical oncocytoma

49 y/o F referred for evaluation of newly detected left adrenal mass. Because of microscopic hematuria, she underwent evaluation with CT scan of abdomen/pelvis and cystoscopy. CT scan detected a right adrenal mass.

Read more on Adrenal cortical oncocytoma…

Primary pigmented nodular adrenal disease (PPNAD), c/w Carney complex

29 y/o F c h/o Carney complex diagnosed on genetic testing with initial atrial myxoma presents for bilateral adrenalectomy for cure of ACTH-independent Cushing’s syndrome.

Adrenal cortical adenoma

53 year old woman with 4.5cm adrenal mass

Metastatic carcinoma, c/w lung primary (adrenal)

49 year old man with 3.1 cm adrenal gland mass

Adrenal cortical carcinoma

28 year old woman with 10.5 cm adrenal mass.

Chest wall hamartoma

Large rib lesion in newborn

Malignant melanoma, nasal primary

50 y/o female with a nasal mass

Leishmaniasis, cutaneous

50 y/o male from the middle east.

Erythema multiforme-like graft-versus-host disease

40 y/o female, status-post bone marrow transplant, with maculopapular rash

Spongiotic dermatitis, c/w acute eczema (acral skin)

50 y/o female with a rash on the palm

Herpes infection, skin

77 y/o male with a red plaque on the left arm

Leukocytoclastic vasculitis

49 y/o female with palpable purpura on the legs

Coma bulla, with eccrine gland necrosis

37 y/o male in the ICU following a severe fall, cutaneous blisters

Diffuse large B-cell lymphoma, immunoblastic variant

75 y/o female with cervical lymphadenopathy

Nodular lymphocyte-predominant hodgkin lymphoma

60 y/o female with known endometrial carcinoma and pelvic lymphadenopathy

Systemic mastocytosis

37 y/o male with urticaria. Bone marrow biopsy.