Virtual Slidebox
Presented by the MGH Pathology Service

Female in her 40’s with bilateral infiltrates and dyspnea

Female in her 40’s with a 2 cm endobronchial lung mass

Male in his 70’s with dyspnea. Note bronchiolocentric granulomas with giant cells, small tufts of OP, peribronchial metaplasia, interstitial fibrosis

Male smoker in his 50’s with patchy pulmonary infiltrates. Note patchy distribution, with scant inflammation around terminal airways, peribronchiolar metaplasia, filling of terminal airways with macrophages, and interstitial fibrosis.

Pregnant female in her 40’s with spontaneous pneumothorax

Female in her 60’s with dyspnea

Male in his 80’s with a left pleural-based mass and rib destruction

Male in his 20’s with a spontaneous pneumothorax

Adolescent female with spontaneous pneumothorax

25 year old woman with erythematous palpable purpura on the lower legs. The extensive eosinophilic infiltrate is unusual and raises the differential diagnosis of erythema elevatum diutinum and possibly a reaction to arthropod assault.

Read more on Leukocytoclastic vasculitis…

46 year old woman with irregular pigmented macule.

52 yo female with multiple 3-4cm scarred hypertrophic red scaly plaques on face, ears, and scalp

30 yo female with non-tender purpuric lesion of left medial thigh with associated left inguinal lymphadenopathy

67 yo female with 1cm painful nodule on the left thigh

81 yo female with 5mm papule with 3mm keratotic core on left arm

48 yo female with axillary rash consisting of linear clusters of tiny papules, some with scale, many with hyperpigmentation

34 yo female with cafe au lait macules

36 y/o with a lesion on the right ear antihelix

50 yo with a lesion superior to patella

13 y/o with a 7 mm irregular pigmented nevus on the right abdomen

23 yo with a pigmented lesion

No history

Adolescent male with 1.3 cm subcutaneous nodule in left cheek

Male in his 60’s with a 1 cm nodule on dorsal surface of right foot. FNA yielded 1 ml of mucoid material

Male in his 40’s with respiratory failure

Adolescent male with spontaneous pneumothorax

Female in her 20’s with severe endometriosis and pulmonary infiltrates

Female in her 60’s with fevers and admission for acute respiratory distress two weeks ago. Note hyaline membranes, proliferative interstitial and intra-alveolar fibrosis, and prominent pneumocytes.

Male in his 20’s with fever, dyspnea, and rash. Note bronchiolar and alveolar mixed inflammation and scattered highly atypical pneumocytes

Male in his 80’s with pleural effusions. Note epithelioid cells in tubuloglandular structures, nests, and strands, and mesenchymal cells with storiform pattern.

Male in his 50’s with recurrent respiratory failure, s/p prior admission to ICU one month ago. Note interstitial fibrosis, hyperplastic pneumocytes, focal fibrin and OP changes, and absence of hyaline membranes.

Read more on Diffuse alveolar damage, late organizing phase…

Male in his 30’s with nodular pulmonary opacities

Female in her 60’s with progressive dyspnea

Female in her 80’s with pleural plaques and a bloody pleural effusion

Female in her 60’s with a seven-year history of chronic, productive cough

Female in her 50’s with dyspnea and bilateral ground-glass opacities

Male in his 60’s with bilateral nodular pulmonary infiltrates. Note branching tongues of fibrous tissue in airspaces and eosinophils.

Female in her 20’s with spontaneous pneumothorax

Male in his 50’s with right knee subcutaneous mass; clinical impression is schwannoma

Male in his 50’s with a T2 bright large mass in right deltoid

Female in her 40’s with a gastric mass

Female in her 40’s with an 8 cm vulvar mass

Female in her 80’s with a lung mass and history of ovarian tumor

Female in her 60’s with a thyroid nodule

Male in his 20’s with a right leg mass

Male in his 40’s with a sacral mass

Female in her 20’s with a right hand mass

Male in his 70’s with a testicular mass

Male in his 20’s who first presented with jaundice and elevated liver enzymes at the age of 14.

Male in his 60’s with a history of fatty liver, ALT 97, AST 73, AIP 148